Identification of Glyceraldehyde-3-Phosphate Dehydrogenase Gene as an Alternative Safe Harbor Locus in Pig Genome

Identification of Glyceraldehyde-3-Phosphate Dehydrogenase Gene as an Alternative Safe Harbor Locus in Pig Genome

The ectopic overexpression of foreign genes in animal genomes is an important strategy for gain-of-function study and establishment of transgenic animal models. Previous studies showed that two loci (<i>Rosa26</i> and <i>pH11</i>) were identified as safe harbor locus in pig g...

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Bibliographic Details
Main Authors: Xiaosong Han, Youcai Xiong, Changzhi Zhao, Shengsong Xie, Changchun Li, Xinyun Li, Xiangdong Liu, Kui Li, Shuhong Zhao, Jinxue Ruan
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Genes
Subjects:
GAPDH
safe harbor
CRISPR/Cas9
homologous recombination
pig
Online Access:https://www.mdpi.com/2073-4425/10/9/660

Internet

https://www.mdpi.com/2073-4425/10/9/660

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