Intermittent Theta-Burst Stimulation Transcranial Magnetic Stimulation Increases GABA in the Medial Prefrontal Cortex: A Preliminary Sham-Controlled Magnetic Resonance Spectroscopy Study in Acute Bipolar Depression

Intermittent Theta-Burst Stimulation Transcranial Magnetic Stimulation Increases GABA in the Medial Prefrontal Cortex: A Preliminary Sham-Controlled Magnetic Resonance Spectroscopy Study in Acute Bipolar Depression

Background: Magnetic resonance spectroscopy (MRS) has been used to identify gamma-aminobutyric acid (GABA) alterations in mood disorders, particularly in the medial prefrontal cortex (mPFC) where decreased concentrations have been associated with anhedonia. In major depressive disorder (MDD), prior...

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Bibliographic Details
Main Authors: Chad Diederichs, Marilena M. DeMayo, Jaeden Cole, Lakshmi N. Yatham, Ashley D. Harris, Alexander McGirr
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Psychiatry
Subjects:
repetitive transcranial magnetic stimulation
intermittent theta burst stimulation
bipolar disorder
bipolar depression
magnetic resonance spectroscopy
gamma-aminobutyric acid
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.665402/full

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https://www.frontiersin.org/articles/10.3389/fpsyt.2021.665402/full

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