Label-free detection of insulin and glucagon within human islets of Langerhans using Raman spectroscopy.

Intrahepatic transplantation of donor islets of Langerhans is a promising therapy for patients with type 1 diabetes. It is of critical importance to accurately monitor islet quality before transplantation, which is currently done by standard histological methods that are performed off-line and requi...

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Bibliographic Details
Main Authors: Janneke Hilderink, Cees Otto, Cees Slump, Aufried Lenferink, Marten Engelse, Clemens van Blitterswijk, Eelco de Koning, Marcel Karperien, Aart van Apeldoorn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3805587?pdf=render