Optimal Pipette Resistance, Seal Resistance, and Zero-Current Membrane Potential for Loose Patch or Breakthrough Whole-Cell Recording in vivo

In vivo loose patch and breakthrough whole-cell recordings are useful tools for investigating the intrinsic and synaptic properties of neurons. However, the correlation among pipette resistance, seal condition, and recording time is not thoroughly clear. Presently, we investigated the recording time...

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Bibliographic Details
Main Authors: Linqing Yan, Qi Fang, Xingui Zhang, Bowan Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Neural Circuits
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fncir.2020.00034/full