Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics.

Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics.

During tissue development, multipotent progenitors differentiate into specific cell types in characteristic spatial and temporal patterns. We addressed the mechanism linking progenitor identity and differentiation rate in the neural tube, where motor neuron (MN) progenitors differentiate more rapidl...

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Bibliographic Details
Main Authors: Andreas Sagner, Zachary B Gaber, Julien Delile, Jennifer H Kong, David L Rousso, Caroline A Pearson, Steven E Weicksel, Manuela Melchionda, S Neda Mousavy Gharavy, James Briscoe, Bennett G Novitch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-02-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.2003127

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https://doi.org/10.1371/journal.pbio.2003127

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