Plant-derived secondary metabolites as the main source of efflux pump inhibitors and methods for identification

The upsurge of multiple drug resistance (MDR) bacteria substantially diminishes the effectiveness of antibiotic arsenal and therefore intensifies the rate of therapeutic failure. The major factor in MDR is efflux pump-mediated resistance. A unique pump can make bacteria withstand a wide range of str...

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Bibliographic Details
Main Authors: Armel Jackson Seukep, Victor Kuete, Lutfun Nahar, Satyajit D. Sarker, Mingquan Guo
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S209517791930646X