Organic carbon monoxide prodrug, BW-CO-111, in protection against chemically-induced gastric mucosal damage

Organic carbon monoxide prodrug, BW-CO-111, in protection against chemically-induced gastric mucosal damage

Metal-based carbon monoxide (CO)-releasing molecules have been shown to exert anti-inflammatory and anti-oxidative properties maintaining gastric mucosal integrity. We are interested in further development of metal-free CO-based therapeutics for oral administration. Thus, we examine the protective e...

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Bibliographic Details
Main Authors: Dominik Bakalarz, Marcin Surmiak, Xiaoxiao Yang, Dagmara Wójcik, Edyta Korbut, Zbigniew Śliwowski, Grzegorz Ginter, Grzegorz Buszewicz, Tomasz Brzozowski, Jakub Cieszkowski, Urszula Głowacka, Katarzyna Magierowska, Zhixiang Pan, Binghe Wang, Marcin Magierowski
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Gastroprotection
Carbon monoxide
Prodrug
Anti-inflammation
NSAID
Ethanol
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383520306882

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http://www.sciencedirect.com/science/article/pii/S2211383520306882

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