Exocyst-mediated membrane trafficking of the lissencephaly-associated ECM receptor dystroglycan is required for proper brain compartmentalization

Exocyst-mediated membrane trafficking of the lissencephaly-associated ECM receptor dystroglycan is required for proper brain compartmentalization

To assemble a brain, differentiating neurons must make proper connections and establish specialized brain compartments. Abnormal levels of cell adhesion molecules disrupt these processes. Dystroglycan (Dg) is a major non-integrin cell adhesion receptor, deregulation of which is associated with drama...

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Bibliographic Details
Main Authors: Andriy S Yatsenko, Mariya M Kucherenko, Yuanbin Xie, Henning Urlaub, Halyna R Shcherbata
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-02-01
Series:eLife
Subjects:
dystroglycan
cobblestone lissencephaly
exocyst
differentiating neurons
neuronal Dg interactome
brain neuropils
Online Access:https://elifesciences.org/articles/63868

Internet

https://elifesciences.org/articles/63868

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