Harnessing PTEN’s Growth Potential in Neuronal Development and Disease
PTEN is a powerful regulator of neuronal growth. It globally suppresses axon extension and branching during both nervous system development and regeneration, by antagonizing growth-promoting PI3K/PI(3,4,5)P 3 signaling. We recently identified that the transmembrane protein PRG2/LPPR3 functions as a...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2020-09-01
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Series: | Neuroscience Insights |
Online Access: | https://doi.org/10.1177/2633105520959056 |