Cigarette smoke induced airway inflammation is independent of NF-κB signalling.

COPD is an inflammatory lung disease largely associated with exposure to cigarette smoke (CS). The mechanism by which CS leads to the pathogenesis of COPD is currently unclear; it is known however that many of the inflammatory mediators present in the COPD lung can be produced via the actions of the...

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Main Authors: Joseph M D Rastrick, Christopher S Stevenson, Suffwan Eltom, Megan Grace, Meirion Davies, Iain Kilty, Steven M Evans, Manolis Pasparakis, Matthew C Catley, Toby Lawrence, Ian M Adcock, Maria G Belvisi, Mark A Birrell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3551940?pdf=render