The Effect of Polymeric Nanoparticles on Biocompatibility of Carrier Red Blood Cells.

Red blood cells (RBCs) can be used for vascular delivery of encapsulated or surface-bound drugs and carriers. Coupling to RBC prolongs circulation of nanoparticles (NP, 200 nm spheres, a conventional model of polymeric drug delivery carrier) enabling their transfer to the pulmonary vasculature witho...

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Bibliographic Details
Main Authors: Daniel Pan, Omayra Vargas-Morales, Blaine Zern, Aaron C Anselmo, Vivek Gupta, Michael Zakrewsky, Samir Mitragotri, Vladimir Muzykantov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4803339?pdf=render