Targeted deletion of endothelial lipase increases HDL particles with anti-inflammatory properties both in vitro and in vivo

Targeted deletion of endothelial lipase increases HDL particles with anti-inflammatory properties both in vitro and in vivo

Previous studies have shown that targeted deletion of endothelial lipase (EL) markedly increases the plasma high density lipoprotein cholesterol (HDL-C) level in mice. However, little is known about the functional quality of HDL particles after EL inhibition. Therefore, the present study assessed th...

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Bibliographic Details
Main Authors: Tetsuya Hara, Tatsuro Ishida, Yoko Kojima, Hanayo Tanaka, Tomoyuki Yasuda, Masakazu Shinohara, Ryuji Toh, Ken-ichi Hirata
Format: Article
Language:English
Published: Elsevier 2011-01-01
Series:Journal of Lipid Research
Subjects:
high density lipoprotein
inflammation
lipopolysaccharide
endotoxin shock
adhesion molecule
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520404961

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http://www.sciencedirect.com/science/article/pii/S0022227520404961

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