Molecular features and genetic markers of gastrointestinal stromal tumors

Molecular features and genetic markers of gastrointestinal stromal tumors

Gastrointestinal stromal tumors (GISTs) are the most spread mesenchymal tumors located within the gastrointestinal tract that have particular clinico-morphological, immunohistochemical and molecular characteristics. The distinguishing mark of GISTs is the presence of the cell-surface antigen CD117 (...

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Bibliographic Details
Main Authors: N. N. Mazurenko, I. МЮ Tsyganova
Format: Article
Language:Russian
Published: ABV-press 2015-06-01
Series:Uspehi Molekulârnoj Onkologii
Subjects:
gastrointestinal stromal tumors
mutations
kit
pdgfra
braf
sdh
targeted therapy
tyrosine kinase inhibitors
imatinib
Online Access:https://umo.abvpress.ru/jour/article/view/23

Internet

https://umo.abvpress.ru/jour/article/view/23

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