Immunization with a live attenuated H7N9 influenza vaccine protects mice against lethal challenge.

The emergence of severe cases of human influenza A (H7N9) viral infection in China in the spring of 2003 resulted in a global effort to rapidly develop an effective candidate vaccine. In this study, a cold-adapted (ca), live attenuated monovalent reassortant influenza H7N9 virus (Ah01/AA ca) was gen...

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Bibliographic Details
Main Authors: Xiaolan Yang, Jianyu Zhao, Cheng Wang, Yueqiang Duan, Zhongpeng Zhao, Rui Chen, Liangyan Zhang, Li Xing, Chengcai Lai, Shaogeng Zhang, Xiliang Wang, Penghui Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4401572?pdf=render