Assessing Transcriptome Quality in Patch-Seq Datasets

Assessing Transcriptome Quality in Patch-Seq Datasets

Patch-seq, combining patch-clamp electrophysiology with single-cell RNA-sequencing (scRNAseq), enables unprecedented access to a neuron's transcriptomic, electrophysiological, and morphological features. Here, we present a re-analysis of five patch-seq datasets, representing cells from ex vivo...

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Bibliographic Details
Main Authors: Shreejoy J. Tripathy, Lilah Toker, Claire Bomkamp, B. Ogan Mancarci, Manuel Belmadani, Paul Pavlidis
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
gene expression profiling
patch-clamp techniques
sequencing data analysis
neurophysiology
meta-analysis
ion channels
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00363/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2018.00363/full

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