Identification of Immune Responses to Japanese Encephalitis Virus Specific T Cell Epitopes

Identification of Immune Responses to Japanese Encephalitis Virus Specific T Cell Epitopes

Background: Due to the similarity between the dengue (DENV) and the Japanese encephalitis virus (JEV) there is potential for immune cross-reaction. We sought to identify T cell epitopes that are specific to JEV and do not cross react with DENV.Methodology: 20mer peptides were synthesized from region...

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Bibliographic Details
Main Authors: Pradeep Darshana Pushpakumara, Chandima Jeewandara, Ayesha Wijesinghe, Laksiri Gomes, Graham S. Ogg, Charitha Lakshini Goonasekara, Gathsaurie Neelika Malavige
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Public Health
Subjects:
Japanese encephalitis virus
dengue virus
cross reactive T cell responses
cultured ELISpot assays
highly conserved regions
Online Access:https://www.frontiersin.org/article/10.3389/fpubh.2020.00019/full

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https://www.frontiersin.org/article/10.3389/fpubh.2020.00019/full

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