Pore dilation occurs in TRPA1 but not in TRPM8 channels

<p>Abstract</p> <p>Abundantly expressed in pain-sensing neurons, TRPV1, TRPA1 and TRPM8 are major cellular sensors of thermal, chemical and mechanical stimuli. The function of these ion channels has been attributed to their selective permeation of small cations (e.g., Ca<sup>...

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Bibliographic Details
Main Authors: Faltynek Connie R, Cavanaugh Eric J, Bianchi Bruce R, Kim Donghee, Chen Jun, Kym Philip R, Reilly Regina M
Format: Article
Language:English
Published: SAGE Publishing 2009-01-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/5/1/3