Distinct gene expression profiles characterize cellular responses to palmitate and oleate[S]

Obese individuals are both insulin resistant and have high levels of circulating free fatty acids (FFAs). In cell culture, saturated but not unsaturated fatty acids induce endoplasmic reticulum (ER) stress. We hypothesized that chronic exposure to low dose fatty acids would significantly attenuate t...

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Bibliographic Details
Main Authors: Swapan K. Das, Ashis K. Mondal, Steven C. Elbein
Format: Article
Language:English
Published: Elsevier 2010-08-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520370498