The histone H3 lysine 27-specific demethylase Jmjd3 is required for neural commitment.

Patterns of methylation at lysine 4 and 27 of histone H3 have been associated with states of gene activation and repression that are developmentally regulated and are thought to underlie the establishment of lineage specific gene expression programs. Recent studies have provided fundamental insight...

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Bibliographic Details
Main Authors: Thomas Burgold, Fabio Spreafico, Francesca De Santa, Maria Grazia Totaro, Elena Prosperini, Gioacchino Natoli, Giuseppe Testa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18716661/pdf/?tool=EBI