Adaptation of the AID system for stem cell and transgenic mouse research

The auxin-inducible degron (AID) system is becoming a widely used method for rapid and reversible degradation of target proteins. This system has been successfully used to study gene and protein functions in eukaryotic cells and common model organisms, such as nematode and fruit fly. To date, applic...

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Bibliographic Details
Main Authors: Marina V. Pryzhkova, Michelle J. Xu, Philip W. Jordan
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Stem Cell Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120303792