Gene Therapy Using Plasmid DNA Encoding Vascular Endothelial Growth Factor 164 and Fibroblast Growth Factor 2 Genes for the Treatment of Horse Tendinitis and Desmitis: Case Reports

Gene Therapy Using Plasmid DNA Encoding Vascular Endothelial Growth Factor 164 and Fibroblast Growth Factor 2 Genes for the Treatment of Horse Tendinitis and Desmitis: Case Reports

In this clinical study, for the first time we used the direct gene therapy to restore severe injuries of the suspensory ligament branch and superficial digital flexor tendon in horses (Equus caballus). We injected the plasmid DNA encoding two therapeutic species-specific growth factors: vascular end...

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Bibliographic Details
Main Authors: Milomir Kovac, Yaroslav A. Litvin, Ruslan O. Aliev, Elena Yu Zakirova, Catrin S. Rutland, Andrey P. Kiyasov, Albert A. Rizvanov
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Veterinary Science
Subjects:
gene therapy
tendon
suspensory ligament
horse
vascular endothelial growth factor
fibroblast growth factor
Online Access:http://journal.frontiersin.org/article/10.3389/fvets.2017.00168/full

Internet

http://journal.frontiersin.org/article/10.3389/fvets.2017.00168/full

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