Substrate transport and anion permeation proceed through distinct pathways in glutamate transporters
Advances in structure-function analyses and computational biology have enabled a deeper understanding of how excitatory amino acid transporters (EAATs) mediate chloride permeation and substrate transport. However, the mechanism of structural coupling between these functions remains to be established...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-06-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/25850 |