Selective Pressures on Human Cancer Genes along the Evolution of Mammals

Cancer is a disease driven by both somatic mutations that increase survival and proliferation of cell lineages and the evolution of genes associated with cancer risk in populations. Several genes associated with cancer in humans, hereafter cancer genes, show evidence of germline positive selection a...

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Bibliographic Details
Main Authors: Alberto Vicens, David Posada
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/9/12/582