The epoxygenases CYP2J2 activates the nuclear receptor PPARalpha in vitro and in vivo.

Peroxisome proliferator-activated receptors (PPARs) are a family of three (PPARalpha, -beta/delta, and -gamma) nuclear receptors. In particular, PPARalpha is involved in regulation of fatty acid metabolism, cell growth and inflammation. PPARalpha mediates the cardiac fasting response, increasing fat...

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Bibliographic Details
Main Authors:	Jessica A Wray, Mary C Sugden, Darryl C Zeldin, Gemma K Greenwood, Salma Samsuddin, Laura Miller-Degraff, J Alyce Bradbury, Mark J Holness, Timothy D Warner, David Bishop-Bailey
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2009-10-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC2756622?pdf=render

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http://europepmc.org/articles/PMC2756622?pdf=render

The epoxygenases CYP2J2 activates the nuclear receptor PPARalpha in vitro and in vivo.

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