Triclosan-induced glycolysis drives inflammatory activation in microglia via the Akt/mTOR/HIF 1α signaling pathway

Triclosan-induced glycolysis drives inflammatory activation in microglia via the Akt/mTOR/HIF 1α signaling pathway

Exposure to triclosan (TCS) has been implicated in neurotoxicity including autism spectrum disorders in vivo and oxidative stress and cell apoptosis in vitro. Thus, the molecular mechanisms underlying TCS-induced neurotoxicity warrants further research. In this study, we try to address the mode of a...

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Bibliographic Details
Main Authors: Jieyu Liu, Rui Feng, Dan Wang, Taoguang Huo, Hong Jiang
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Triclosan
Inflammatory cytokines
Glycolysis
Akt/mTOR/HIF 1α pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651321007764

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http://www.sciencedirect.com/science/article/pii/S0147651321007764

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