BRCA1/2 genetic background-based therapeutic tailoring of human ovarian cancer: hope or reality?

<p>Abstract</p> <p>Ovarian epithelial tumors are an hallmark of hereditary cancer syndromes which are related to the germ-line inheritance of cancer predisposing mutations in BRCA1 and BRCA2 genes. Although these genes have been associated with multiple different physiologic functi...

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Bibliographic Details
Main Authors: Tagliaferri Pierosandro, Ventura Monica, Baudi Francesco, Cucinotto Iole, Arbitrio Mariamena, Di Martino Maria, Tassone Pierfrancesco
Format: Article
Language:English
Published: BMC 2009-10-01
Series:Journal of Ovarian Research
Online Access:http://www.ovarianresearch.com/content/2/1/14