Exploring the Antimicrobial Action of Quaternary Amines against Acinetobacter baumannii

Quaternary amine compounds (QAC) are potent antimicrobials used to prevent the spread of pathogenic bacteria. While they are known for their membrane-damaging properties, QAC action has been suggested to extend beyond the surface to intracellular targets. Here we characterize the range of action of...

Full description

Bibliographic Details
Main Authors: Gregory A. Knauf, Ashley L. Cunningham, Misha I. Kazi, Ian M. Riddington, Alexander A. Crofts, Vincent Cattoir, M. Stephen Trent, Bryan W. Davies, John J. Mekalanos
Format: Article
Language:English
Published: American Society for Microbiology 2018-02-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/9/1/e02394-17