Sperm modulate uterine immune parameters relevant to embryo implantation and reproductive success in mice

Components of the seminal fluid are required for specific gene expression and immune changes in the uterus following mating, but the role that sperm play in this process has remained unclear. Here, John Schjenken et al. compare female mice mated to intact and vasectomized males and show that sperm a...

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Bibliographic Details
Main Authors: John E. Schjenken, David J. Sharkey, Ella S. Green, Hon Yeung Chan, Ricky A. Matias, Lachlan M. Moldenhauer, Sarah A. Robertson
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02038-9