Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells
<p>The vascular smooth muscle cell (VSMC) phenotypic switch is a key pathophysiological change in various cardiovascular diseases, such as aortic dissection (AD), with a high morbidity. Polycystin-1 (PC1) is significantly downregulated in the VSMCs of AD patients. PC1 is an integral membrane g...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
PAGEPress Publications
2016-12-01
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Series: | European Journal of Histochemistry |
Subjects: | |
Online Access: | http://www.ejh.it/index.php/ejh/article/view/2711 |