Striatal Cholinergic Interneurons in a Knock-in Mouse Model of L-DOPA-Responsive Dystonia

Striatal cholinergic dysfunction is a common phenotype associated with various forms of dystonia in which anti-cholinergic drugs have some therapeutic benefits. However, the underlying substrate of striatal cholinergic defects in dystonia remain poorly understood. In this study, we used a recently d...

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Bibliographic Details
Main Authors: Gul Yalcin-Cakmakli, Samuel J. Rose, Rosa M. Villalba, Lagena Williams, Hyder A. Jinnah, Ellen J. Hess, Yoland Smith
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Systems Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnsys.2018.00028/full