Differentiation, functions, and roles of T follicular regulatory cells in autoimmune diseases
Abstract T follicular helper cells participate in stimulating germinal center (GC) formation and supporting B cell differentiation and autoantibody production. However, T follicular regulatory (Tfr) cells suppress B cell activation. Since changes in the number and functions of Tfr cells lead to dysr...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-05-01
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Series: | Inflammation and Regeneration |
Subjects: | |
Online Access: | https://doi.org/10.1186/s41232-021-00164-9 |