Ex Vivo Expansion of Hematopoietic Stem Cells for Therapeutic Purposes: Lessons from Development and the Niche

Expansion of hematopoietic stem cells (HSCs) for therapeutic purposes has been a “holy grail„ in the field for many years. Ex vivo expansion of HSCs can help to overcome material shortage for transplantation purposes and genetic modification protocols. In this review, we summariz...

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Bibliographic Details
Main Authors: Parisa Tajer, Karin Pike-Overzet, Sagrario Arias, Menzo Havenga, Frank J.T. Staal
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/2/169