Statistical Correlations between HPLC Activity-Based Profiling Results and NMR/MS Microfraction Data to Deconvolute Bioactive Compounds in Mixtures

Statistical Correlations between HPLC Activity-Based Profiling Results and NMR/MS Microfraction Data to Deconvolute Bioactive Compounds in Mixtures

Recent approaches in natural product (NP) research are leading toward the discovery of bioactive chemical entities at the microgram level. In comparison to classical large scale bioassay-guided fractionation, the use of LC-MS metabolite profiling in combination with microfractionation for both bioac...

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Bibliographic Details
Main Authors: Samuel Bertrand, Antonio Azzollini, Andreas Nievergelt, Julien Boccard, Serge Rudaz, Muriel Cuendet, Jean-Luc Wolfender
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Molecules
Subjects:
microfractionation
biological profiling
correlation analysis
quinone reductase induction
metabolomics
Online Access:http://www.mdpi.com/1420-3049/21/3/259

Internet

http://www.mdpi.com/1420-3049/21/3/259

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