Activin signaling in the pathogenesis and therapy of neuropsychiatric diseases

Activins are members of the transforming growth factor β (TGFβ) family and serve as multifunctional regulatory proteins in many tissues and organs. In the brain, activin A, which is formed by two disulfide-linked βA subunits, is recognized as the predominant player in activin signaling. Over the las...

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Bibliographic Details
Main Authors: Andrea eLink, Fang eZheng, Christian eAlzheimer
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00032/full