CREB1 and ATF1 Negatively Regulate Glutathione Biosynthesis Sensitizing Cells to Oxidative Stress

The cAMP response element binding protein (CREB) family activating transcription factor 1 (ATF1) and cAMP response element binding protein 1 (CREB1) have been reported in a diverse group of tumors, however, the mechanistic basis for this remains unclear. Here we found that CREB1 and ATF1 unexpectedl...

Full description

Bibliographic Details
Main Authors: Lina Zhao, Wenjun Xia, Peng Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
GSH
ROS
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.698264/full