Comprehensive Somatic Copy Number Analysis Using Aqueous Humor Liquid Biopsy for Retinoblastoma

Comprehensive Somatic Copy Number Analysis Using Aqueous Humor Liquid Biopsy for Retinoblastoma

Aqueous humor (AH) liquid biopsy has been established as a surrogate tumor biopsy for retinoblastoma (RB). Previous AH studies have focused on highly recurrent RB somatic copy number alterations (SCNAs) including gain of 1q, 2p, 6p, and loss of 13q and 16q. In this retrospective study, we provide a...

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Bibliographic Details
Main Authors: Mary E. Kim, Ashley Polski, Liya Xu, Rishvanth K. Prabakar, Chen-Ching Peng, Mark W. Reid, Rachana Shah, Peter Kuhn, David Cobrinik, James Hicks, Jesse L. Berry
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
retinoblastoma
aqueous humor
liquid biopsy
cell-free DNA
circulating tumor DNA
SCNA
Online Access:https://www.mdpi.com/2072-6694/13/13/3340

Internet

https://www.mdpi.com/2072-6694/13/13/3340

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