A Painful Beginning: Early Life Surgery Produces Long-Term Behavioral Disruption in the Rat

Early life surgery produces peripheral nociceptive activation, inflammation, and stress. Early life nociceptive input and inflammation have been shown to produce long-term processing changes that are not restricted to the dermatome of injury. Additionally stress has shown long-term effects on anxiet...

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Bibliographic Details
Main Authors: Douglas G. Ririe, James C. Eisenach, Thomas J. Martin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2021.630889/full