GC-Content Normalization for RNA-Seq Data

<p>Abstract</p> <p>Background</p> <p>Transcriptome sequencing (RNA-Seq) has become the assay of choice for high-throughput studies of gene expression. However, as is the case with microarrays, major technology-related artifacts and biases affect the resulting expression...

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Bibliographic Details
Main Authors: Risso Davide, Schwartz Katja, Sherlock Gavin, Dudoit Sandrine
Format: Article
Language:English
Published: BMC 2011-12-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/480