The Impact of a Non-Functional Thyroid Receptor Beta upon Triiodotironine-Induced Cardiac Hypertrophy in Mice

The Impact of a Non-Functional Thyroid Receptor Beta upon Triiodotironine-Induced Cardiac Hypertrophy in Mice

Background/Aims: Thyroid hormone (TH) signalling is critical for heart function. The heart expresses thyroid hormone receptors (THRs); THRα1 and THRβ1. We aimed to investigate the regulation mechanisms of the THRβ isoform, its association with gene expression changes and implications for cardiac fun...

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Bibliographic Details
Main Authors: Güínever Eustáquio do Império, Isalira Peroba Ramos, Letícia Aragão Santiago, Guilherme Faria Pereira, Norma Aparecida dos Santos Almeida, Cesar Seigi Fuziwara, Carmen C. Pazos-Moura, Edna Teruko Kimura, Emerson Lopes Olivares, Tania Maria Ortiga-Carvalho
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Thyroid Hormone
Cardiac hypertrophy
Thyroid hormone receptor
MicroRNA
Transgenic mice
Online Access:http://www.karger.com/Article/FullText/430370

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http://www.karger.com/Article/FullText/430370

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