Increased DOI-Induced Wet-Dog Shakes in Adrenocorticotropic Hormone–Treated Rats Are Not Affected by Chronic Imipramine Treatment: Possible Involvement of Enhanced 5-HT2A–Receptor Expression in the Frontal Cortex

Increased DOI-Induced Wet-Dog Shakes in Adrenocorticotropic Hormone–Treated Rats Are Not Affected by Chronic Imipramine Treatment: Possible Involvement of Enhanced 5-HT2A–Receptor Expression in the Frontal Cortex

We examined the influence of imipramine, a traditional tricyclic antidepressant, on the binding to serotonin (5-HT)2receptors and levels of 5-HT2A–receptor mRNA in the frontal cortex of rats treated with adrenocorticotropic hormone (ACTH). Chronic treatment with ACTH significantly increased the bind...

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Bibliographic Details
Main Authors: Yoshihisa Kitamura, Kazuhiko Shibata, Kozue Akiyama, Shizue Kimoto, Yoshika Fujitani, Kouhei Kitagawa, Hirotaka Kanzaki, Mamoru Ouchida, Kenji Shimizu, Hiromu Kawasaki, Toshiaki Sendo, Yutaka Gomita
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319315415

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http://www.sciencedirect.com/science/article/pii/S1347861319315415

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