A 5′-tRNA halve, tiRNA-Gly promotes cell proliferation and migration via binding to RBM17 and inducing alternative splicing in papillary thyroid cancer

A 5′-tRNA halve, tiRNA-Gly promotes cell proliferation and migration via binding to RBM17 and inducing alternative splicing in papillary thyroid cancer

Abstract Background tRNA-derived small noncoding RNAs (sncRNAs) are mainly categorized into tRNA halves (tiRNAs) and fragments (tRFs). Biological functions of tiRNAs in human solid tumor are attracting more and more attention, but researches concerning the mechanisms in tiRNAs-mediated tumorigenesis...

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Bibliographic Details
Main Authors: Litao Han, Hejing Lai, Yichen Yang, Jiaqian Hu, Zhe Li, Ben Ma, Weibo Xu, Wanlin Liu, Wenjun Wei, Duanshu Li, Yu Wang, Qiwei Zhai, Qinghai Ji, Tian Liao
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
tiRNA-Gly
RBM17
Alternative splicing
MAP4K4
Papillary thyroid carcinoma
Online Access:https://doi.org/10.1186/s13046-021-02024-3

Internet

https://doi.org/10.1186/s13046-021-02024-3

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