Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species.

Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species.

Withaferin A (WA), a promising anticancer constituent of Ayurvedic medicinal plant Withania somnifera, inhibits growth of MDA-MB-231 and MCF-7 human breast cancer cells in culture and MDA-MB-231 xenografts in vivo in association with apoptosis induction, but the mechanism of cell death is not fully...

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Bibliographic Details
Main Authors: Eun-Ryeong Hahm, Michelle B Moura, Eric E Kelley, Bennett Van Houten, Sruti Shiva, Shivendra V Singh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3154436?pdf=render

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http://europepmc.org/articles/PMC3154436?pdf=render

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