Increased B3GALNT2 in hepatocellular carcinoma promotes macrophage recruitment via reducing acetoacetate secretion and elevating MIF activity

Increased B3GALNT2 in hepatocellular carcinoma promotes macrophage recruitment via reducing acetoacetate secretion and elevating MIF activity

Abstract Background Hepatocellular carcinoma (HCC) ranks as the sixth most prevalent cancer and the third leading cause of tumor-related death, so it is urgently needed to discover efficient markers and targets for therapy. β-1,3-N-acetylgalactosaminyltransferase II (B3GALNT2) belongs to the β-1,3-g...

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Bibliographic Details
Main Authors: Tianxiao Yang, Yilin Wang, Wenjuan Dai, Xixi Zheng, Jing Wang, Shushu Song, Lan Fang, Jiangfan Zhou, Weicheng Wu, Jianxin Gu
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Journal of Hematology & Oncology
Subjects:
Hepatocellular carcinoma
B3GALNT2
Macrophage recruitment
Acetoacetate
MIF
Online Access:http://link.springer.com/article/10.1186/s13045-018-0595-3

Internet

http://link.springer.com/article/10.1186/s13045-018-0595-3

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