Mitochondrial DNA alteration in primary and metastatic colorectal cancer: Different frequency and association with selected clinicopathological and molecular markers

This study attempts to determine whether primary tumor tissue could reliably represent metastatic colorectal cancer in therapy-guiding analysis of mitochondrial microsatellite instability. Therefore, we investigated the concordance of microsatellite instability in D310, D514, and D16184 (mitochondri...

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Bibliographic Details
Main Authors: Britta Kleist, Thuja Meurer, Micaela Poetsch
Format: Article
Language:English
Published: IOS Press 2017-03-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317692246