Preliminary modeling of the perfusion culture of mammalian cells with a spinfilter as retention device

Specific equations describing the behavior of cell growth and the filtration mechanism of a perfusion culture in stirred tank fermentors at 30 L scale were derived from basic equations for mass balance and mechanical energy in a spinfilter. These equations, when used for modeling the operation proce...

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Bibliographic Details
Main Authors: Luis Y Hernández, Abel González, Jorge Bouza, Orestes Mayo, Elena Kulich, Guido Riera
Format: Article
Language:English
Published: Elfos Scientiae
Series:Biotecnología Aplicada
Subjects:
Online Access:http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522010000100004&lng=en&tlng=en