Preliminary modeling of the perfusion culture of mammalian cells with a spinfilter as retention device
Specific equations describing the behavior of cell growth and the filtration mechanism of a perfusion culture in stirred tank fermentors at 30 L scale were derived from basic equations for mass balance and mechanical energy in a spinfilter. These equations, when used for modeling the operation proce...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elfos Scientiae
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Series: | Biotecnología Aplicada |
Subjects: | |
Online Access: | http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522010000100004&lng=en&tlng=en |