Low-cost synthesis of peptide libraries and their use for binding studies via temperature-related intensity change

Summary: Protein-peptide interactions are involved in many fundamental cellular functions and constitute promising drug targets. Here, we provide a detailed protocol for the cost-effective preparation of a cellulose-based solid support for synthesis of nanoscale to micromolar-scale peptide libraries...

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Bibliographic Details
Main Authors: Clemens Schulte, Vladimir Khayenko, Amit Jean Gupta, Hans Michael Maric
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721003129