Multiple Evolutionarily Conserved Domains of Cap2 Are Required for Promoter Recruitment and Iron Homeostasis Gene Regulation

Iron is an essential micronutrient for living cells. Candida albicans, the predominant human fungal pathogen, thrives under diverse environments with vastly different iron levels in the mammalian host. Therefore, to tightly control iron homeostasis, C. albicans has evolved a set of transcriptional r...

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Bibliographic Details
Main Authors: Manjit Kumar Srivastav, Neha Agarwal, Krishnamurthy Natarajan
Format: Article
Language:English
Published: American Society for Microbiology 2018-08-01
Series:mSphere
Subjects:
Online Access:https://doi.org/10.1128/mSphere.00370-18