Knockdown of myostatin expression by RNAi enhances muscle growth in transgenic sheep.

Myostatin (MSTN) has been shown to be a negative regulator of skeletal muscle development and growth. MSTN dysfunction therefore offers a strategy for promoting animal growth performance in livestock production. In this study, we investigated the possibility of using RNAi-based technology to generat...

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Bibliographic Details
Main Authors: Shengwei Hu, Wei Ni, Wujiafu Sai, Ha Zi, Jun Qiao, Pengyang Wang, Jinliang Sheng, Chuangfu Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3603981?pdf=render