A tight balance of Karyopherin β1 expression is required in cervical cancer cells

Abstract Background Karyopherin β1 (Kpnβ1) is the main nuclear import protein involved in the transport of cargoes from the cytoplasm into the cell nucleus. Previous research has found Kpnβ1 to be significantly overexpressed in cervical cancer and other cancer tissues, and further studies showed tha...

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Bibliographic Details
Main Authors: Sarah Carden, Pauline van der Watt, Alicia Chi, Aderonke Ajayi-Smith, Katie Hadley, Virna D. Leaner
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-018-5044-8