A novel Lnc408 maintains breast cancer stem cell stemness by recruiting SP3 to suppress CBY1 transcription and increasing nuclear β-catenin levels

A novel Lnc408 maintains breast cancer stem cell stemness by recruiting SP3 to suppress CBY1 transcription and increasing nuclear β-catenin levels

Abstract Tumor initiation, development, and relapse may be closely associated with cancer stem cells (CSCs). The complicated mechanisms underlying the maintenance of CSCs are keeping in illustration. Long noncoding RNAs (lncRNAs), due to their multifunction in various biological processes, have been...

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Bibliographic Details
Main Authors: Siyang Wen, Yilu Qin, Rui Wang, Liping Yang, Huan Zeng, Pengpeng Zhu, Qiao Li, Yuxiang Qiu, Shanchun Chen, Yongcan Liu, Yixuan Hou, Xi Tang, Manran Liu, Gang Tu
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03708-6

Internet

https://doi.org/10.1038/s41419-021-03708-6

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